Displaying Alfin-like Family from Maize  
Information about Alfin-like family
The Alfin1-like family is first described by its founding member, Alfin1. The cDNA of Alfin1 was obtained by differential screening of a poly(A)+ library from salt-tolerant alfalfa cells, which encodes a protein with a Cys4 and His/Cys3 putative zinc-binding domain. The putative consensus binding site for Alfin1 is shown to contain two to five G-rich triplets with the conserved core of GNGGTG or GTGGNG (PMID:9869418). Alfin1-binding sites occur in promoters of genes expressed in roots of a wide variety of plant species. Overexpression of Alfin1 in transgenic alfalfa plants driven by the CaMV 35S promoter confers a many-fold increase in root growth under normal and saline conditions and does not adversely affect shoot growth (PMID:10750899). More recent research has purported that the zinc finger motif in Alfin1 is actually a canonical plant homeodomain (PHD) finger, which has not been implicated in DNA binding in other proteins thus far. Further studies are needed to determine whether Alfin1 binds to DNA through the PHD finger or via another unidentified motif. Alfin1-like proteins in Arabidopsis thaliana have been shown to localize to the nucleus and bind to H3K4me3/2 via plant homeodomain (PHD) fingers (PMID:19154204).
Pubmed Links: 9869418     10750899     19154204     

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Protein Name
Gene Name
Gene Id
[ MaizeGDB ]
DNA Binding Preferences
Binding SiteNFM
in TFome
ZmALF1GRMZM2G148810VIEW (1) Available
ZmALF2GRMZM2G063864VIEW (1) Available
ZmALF4GRMZM2G153087 Available
ZmALF5GRMZM2G016817VIEW (1) Available
ZmALF6GRMZM2G115424 Available
ZmALF7GRMZM2G107807VIEW (1) Available
ZmALF8GRMZM2G172001VIEW (1) Available
ZmALF9GRMZM2G017142 Available
ZmALF10GRMZM2G050495VIEW (2) Available
ZmALF11GRMZM2G158918 Available
ZmALF12GRMZM5G893976VIEW (1) Available
ZmALF13GRMZM2G080917VIEW (1) Available
ZmALF14GRMZM2G156088VIEW (1) Available
ZmALF15AC225147.4_FG003VIEW (1) Available
ZmALF16GRMZM2G016564VIEW (1)
ZmALF17GRMZM2G110952VIEW (1) Available
ZmALF18GRMZM2G008259VIEW (1) Available
ZmALF19GRMZM2G047316 Available
19 results found