Displaying Alfin-like Family from Rice  
Information about Alfin-like family
The Alfin1-like family is first described by its founding member, Alfin1. The cDNA of Alfin1 was obtained by differential screening of a poly(A)+ library from salt-tolerant alfalfa cells, which encodes a protein with a Cys4 and His/Cys3 putative zinc-binding domain. The putative consensus binding site for Alfin1 is shown to contain two to five G-rich triplets with the conserved core of GNGGTG or GTGGNG (PMID:9869418). Alfin1-binding sites occur in promoters of genes expressed in roots of a wide variety of plant species. Overexpression of Alfin1 in transgenic alfalfa plants driven by the CaMV 35S promoter confers a many-fold increase in root growth under normal and saline conditions and does not adversely affect shoot growth (PMID:10750899). More recent research has purported that the zinc finger motif in Alfin1 is actually a canonical plant homeodomain (PHD) finger, which has not been implicated in DNA binding in other proteins thus far. Further studies are needed to determine whether Alfin1 binds to DNA through the PHD finger or via another unidentified motif. Alfin1-like proteins in Arabidopsis thaliana have been shown to localize to the nucleus and bind to H3K4me3/2 via plant homeodomain (PHD) fingers (PMID:19154204).
Pubmed Links: 9869418     10750899     19154204     

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Protein Name
[Suggested/Accepted]
Synonym/
Gene Name
Gene Id
[ TIGR ]
RAP-DB Id
[ RAP-DB ]
DNA Binding Preferences
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OsALF2LOC_Os01g66420Os01g0887700
OsALF3LOC_Os02g35600Os02g0564100
OsALF4LOC_Os03g60390Os03g0818250
OsALF5LOC_Os04g36730Os04g0444900
OsALF6LOC_Os05g07040Os05g0163100
OsALF7LOC_Os05g34640Os05g0419100
OsALF8LOC_Os07g12910Os07g0233300
OsALF9LOC_Os07g41740Os07g0608400
OsALF10LOC_Os11g14010Os11g0244800
9 results found