Displaying bHLH Family from Sorghum  
Information about bHLH family
The basic/helix-loop-helix (bHLH) proteins are a superfamily of transcription factors that bind as dimers to specific DNA target sites and that have been wellcharacterized in nonplant eukaryotes as important regulatory components in diverse biological processes. Based on evidence that the bHLH protein PIF3 is a direct phytochrome reaction partner in the photoreceptor signaling network we have undertaken a comprehensive computational analysis of the Arabidopsis genome sequence databases to define the scope and features of the bHLH family. Using a set of criteria derived from a previously defined consensus motif we identified 147 bHLH protein-encoding genes making this one of the largest transcription factor families in Arabidopsis. Phylogenetic analysis of the bHLH domain sequences permits classification of these genes into 21 subfamilies. The evolutionary and potential functional relationships implied by this analysis are supported by other criteria including the chromosomal distribution of these genes relative to duplicated genome segments the conservation of variant exon/intron structural patterns and the predicted DNA binding activities within subfamilies. Considerable diversity in DNA binding site specificity among family members is predicted and marked divergence in protein sequence outside of the conserved bHLH domain is observed. Together with the established propensity of bHLH factors to engage in varying degrees of homodimerization and heterodimerization these observations suggest that the Arabidopsis bHLH proteins have the potential to participate in an extensive set of combinatorial interactions endowing them with the capacity to be involved in the regulation of a multiplicity of transcriptional programs. We provide evidence from yeast two-hybrid and in vitro binding assays that two related phytochrome-interacting members in the Arabidopsis family PIF3 and PIF4 can form both homodimers and heterodimers and that all three dimeric configurations can bind specifically to the G-box DNA sequence motif CACGTG. These data are consistent in principle with the operation of this combinatorial mechanism in Arabidopsis.
(Taken from AGRIS)

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Protein Name
[Suggested/Accepted]
Synonym/
Gene Name
Gene Id
[ Gramene.org ]
DNA Binding Preferences
Binding SiteNFM
Targeting
TFs
Clone
in TFome
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SbbHLH1Sb01g003830
SbbHLH2Sb01g004710
SbbHLH3Sb01g005130
SbbHLH4Sb01g006190
SbbHLH5Sb01g007160
SbbHLH6Sb01g008570
SbbHLH7Sb01g009380
SbbHLH8Sb01g009590
SbbHLH9Sb01g012250
SbbHLH10Sb01g012260
SbbHLH11Sb01g012280
SbbHLH12Sb01g013843
SbbHLH13Sb01g014580
SbbHLH14Sb01g026610
SbbHLH15Sb01g027411
SbbHLH16Sb01g027416
SbbHLH17Sb01g028230
SbbHLH18Sb01g033530
SbbHLH19Sb01g040450
SbbHLH20Sb01g042070
SbbHLH21Sb01g044640
SbbHLH22Sb01g045690
SbbHLH23Sb01g045710
SbbHLH24Sb01g047940
SbbHLH25Sb01g048400
SbbHLH26Sb01g049080
SbbHLH27Sb02g002760
SbbHLH28Sb02g004570
SbbHLH29Sb02g005713
SbbHLH30Sb02g006390
SbbHLH31Sb02g024460
SbbHLH32Sb02g024750
SbbHLH33Sb02g026530
SbbHLH34Sb02g026920
SbbHLH35Sb02g027210
SbbHLH36Sb02g027430
SbbHLH37Sb02g027460
SbbHLH38Sb02g028300
SbbHLH39Sb02g029040
SbbHLH40Sb02g029530
SbbHLH41Sb02g030110
SbbHLH42Sb02g030120
SbbHLH43Sb02g035580
SbbHLH44Sb02g035870
SbbHLH45Sb02g037990
SbbHLH46Sb03g000570
SbbHLH47Sb03g001730
SbbHLH48Sb03g002910
SbbHLH49Sb03g005250
SbbHLH50Sb03g006500
SbbHLH51Sb03g006510
SbbHLH52Sb03g008290
SbbHLH53Sb03g008560
SbbHLH54Sb03g008570
SbbHLH55Sb03g011940
SbbHLH56Sb03g025570
SbbHLH57Sb03g025860
SbbHLH58Sb03g028030
SbbHLH59Sb03g032420
SbbHLH60Sb03g036100
SbbHLH61Sb03g038820
SbbHLH62Sb03g042860
SbbHLH63Sb03g043690
SbbHLH64Sb03g044660
SbbHLH65Sb03g046090
SbbHLH66Sb04g001200
SbbHLH67Sb04g001650
SbbHLH68Sb04g007795
SbbHLH69Sb04g008260
SbbHLH70Sb04g009390
SbbHLH71Sb04g017390
SbbHLH72Sb04g022260
SbbHLH73Sb04g022270
SbbHLH74Sb04g023320
SbbHLH75Sb04g025260
SbbHLH76Sb04g027280
SbbHLH77Sb04g027930
SbbHLH78Sb04g029270
SbbHLH79Sb04g030230
SbbHLH80Sb04g030530
SbbHLH81Sb04g030850
SbbHLH82Sb04g031250
SbbHLH83Sb04g035890
SbbHLH84Sb04g036450
SbbHLH85Sb05g019530
SbbHLH86Sb05g023590
SbbHLH87Sb05g025230
SbbHLH88Sb06g012030
SbbHLH89Sb06g016380
SbbHLH90Sb06g016740
SbbHLH91Sb06g017460
SbbHLH92Sb06g020810
SbbHLH93Sb06g025020
SbbHLH94Sb06g025040
SbbHLH95Sb06g025060
SbbHLH96Sb06g026970
SbbHLH97Sb06g028750
SbbHLH98Sb07g000900
SbbHLH99Sb07g000910
SbbHLH100Sb07g002200
SbbHLH101Sb07g002210
SbbHLH102Sb07g002900
SbbHLH103Sb07g004190
SbbHLH104Sb07g021170
SbbHLH105Sb07g022920
SbbHLH106Sb07g023280
SbbHLH107Sb07g025310
SbbHLH108Sb07g025320
SbbHLH109Sb07g025330
SbbHLH110Sb07g025340
SbbHLH111Sb07g025920
SbbHLH112Sb07g026610
SbbHLH113Sb07g027810
SbbHLH114Sb07g028860
SbbHLH115Sb07g028945
SbbHLH116Sb08g019780
SbbHLH117Sb08g020275
SbbHLH118Sb08g020280
SbbHLH119Sb08g020290
SbbHLH120Sb08g020300
SbbHLH121Sb08g020320
SbbHLH122Sb08g020330
SbbHLH123Sb08g021000
SbbHLH124Sb08g022760
SbbHLH125Sb09g003090
SbbHLH126Sb09g004820
SbbHLH127Sb09g006196
SbbHLH128Sb09g006220
SbbHLH129Sb09g008120
SbbHLH130Sb09g022280
SbbHLH131Sb09g030060
SbbHLH132Sb09g030930
SbbHLH133Sb10g004500
SbbHLH134Sb10g005650
SbbHLH135Sb10g006250
SbbHLH136Sb10g008000
SbbHLH137Sb10g020490
SbbHLH138Sb10g022530
SbbHLH139Sb10g030470
SbbHLH140Sb0010s017130
SbbHLH141Sb0012s004780
SbbHLH142Sb2250s002010
SbbHLH143Sb2273s002010
143 results found