Displaying Trihelix Family from Sugarcane


INFORMATION ABOUT Trihelix FAMILY

GT-2 is a plant transcriptional activator that contains two separate, but similar, trihelix DNA-binding domains. GT-1 is similar to GT-2, although it contains only one of such domains. cDNAs that encode GT-2 were isolated from rice (OS-GT2) and Arabidopsis (AT-GT2). Evidence is presented for the existence of an Arabidopsis gene family that is structurally related to AT-GT2. Two members of this GT2-like family, AT-GTL1 and AT-GTL2, have been isolated and characterized. Their sequences suggest that they evolved by a recent gene duplication event. Both AT-GT2 and AT-GTL genes contain an intron in the amino-terminal trihelix motif, indicating that this DNA-binding domain resulted from exon shuffling. RNA gel blot analysis using AT-GTL1 as a probe revealed four transcripts in the aerial part of the plant. All mRNA levels were significantly higher in siliques, suggesting that this gene family may function in fruit and/or seed development. To date, DNA-binding proteins characterized by the trihelix motif have been described only in plants, and may therefore be involved in plant-specific processes. Our results show that in Arabidopsis thaliana, the trihelix motif is not restricted to the GT-1 and GT-2 DNA-binding proteins.


Protein Name
[ accepted / suggested]
Gene Locus Synonym/
Gene Name
Clone in TFome Genome Browser
ScTHX1 SCEZHR1083C04.g View in Browser
ScTHX2 SCJLST1019B09.g View in Browser
ScTHX3 SCVPRZ3030F10.g View in Browser
ScTHX4 PTSo01028.1 View in Browser
ScTHX5 PTSo01029.1 View in Browser
ScTHX6 PTSo01027.1 View in Browser