GrassTFDB :: Browse Family::Maize

Displaying CCAAT-HAP2 Family from Maize


The CCAAT motif is found in the promoters of many eukaryotic genes. In yeast a single complex of three proteins termed HAP2 HAP3 and HAP5 binds to this sequence and in mammals the three components of the equivalent complex (called variously NF-Y CBF or CP1) are also represented by single genes. Here we report the presence of multiple genes for each of the components of the CCAAT-binding complex HAP2 35 from Arabidopsis. Three independent Arabidopsis HAP subunit 2 (AtHAP2) cDNAs were cloned by functional complementation of a yeast hap2 mutant and two independent forms each of AtHAP3 and AtHAP5 cDNAs were detected in the expressed sequence tag database. Additional homologs (two of AtHAP3 and one of AtHAP5) have been identified from available Arabidopsis genomic sequences. Northern-blot analysis indicated ubiquitous expression for each AtHAP2 and AtHAP5 cDNA in a range of tissues whereas expression of each AtHAP3 cDNA was under developmental and/or environmental regulation. The unexpected presence of multiple forms of each HAP homolog in Arabidopsis compared with the single genes in yeast and vertebrates suggests that the HAP235 complex may play diverse roles in gene transcription in higher plants.

Protein Name
accepted / suggested
Gene Locus Synonym/
Gene Name
Clone in TFome Genome Browser
ZmCA2P1 GRMZM2G026157 CA2P1 View in Browser
ZmCA2P2 GRMZM2G582893 CA2P2 View in Browser
ZmCA2P3 GRMZM2G037630 CA2P3 View in Browser
ZmCA2P4 GRMZM2G040349 CA2P4 View in Browser
ZmCA2P5 GRMZM5G853836 CA2P5 pUT6780 View in Browser
ZmCA2P6 GRMZM5G829103 CA2P6 pUT6566 View in Browser
ZmCA2P7 GRMZM2G126957 CA2P7 pUT6735 View in Browser
ZmCA2P8 GRMZM2G361842 CA2P8 pUT6585 View in Browser
ZmCA2P9 GRMZM5G865626 CA2P9 View in Browser
ZmCA2P10 GRMZM2G165488 CA2P10 pUT6571 View in Browser
ZmCA2P11 GRMZM2G000686 NFYA1 pUT6627 View in Browser
ZmCA2P12 GRMZM2G104396 CA2P12 pUT6582 View in Browser
ZmCA2P13 GRMZM5G857944 CA2P13 pUT6640 View in Browser
ZmCA2P14 GRMZM2G096016 CA2P14 pUT6267 View in Browser
ZmCA2P15 GRMZM2G038303 CA2P15 View in Browser
ZmCA2P16 GRMZM2G091964 CA2P16 pUT6573 View in Browser