GrassTFDB :: Browse Family::Maize

Displaying GRF Family from Maize


Previously, we identified a novel rice gene, GROWTH-REGULATING FACTOR1 (OsGRF1), which encodes a putative transcription factor that appears to play a regulatory role in stem elongation. We now describe the GRF gene family of Arabidopsis thaliana (AtGRF), which comprises nine members. The deduced AtGRF proteins contain the same characteristic regions--the QLQ (Gln, Leu, Gln) and WRC (Trp, Arg, Cys) domains--as do OsGRF1 and related proteins in rice, as well as features indicating a function in transcriptional regulation. Most of the AtGRF genes are strongly expressed in actively growing and developing tissues, such as shoot tips, flower buds, and roots, but weakly in mature stem and leaf tissues. Overexpression of AtGRF1 and AtGRF2 resulted in larger leaves and cotyledons, as well as in delayed bolting of the inflorescence stem when compared to wild-type plants. In contrast, triple insertional null mutants of AtGRF1-AtGRF3 had smaller leaves and cotyledons, whereas single mutants displayed no changes in phenotype and double mutants displayed only minor ones. The alteration of leaf growth in overexpressors and triple mutants was based on an increase or decrease in cell size, respectively. These results indicate that AtGRF proteins play a role in the regulation of cell expansion in leaf and cotyledon tissues.

Protein Name
accepted / suggested
Gene Locus Synonym/
Gene Name
Clone in TFome Genome Browser
ZmGRF1 GRMZM2G178261 GRFTF1 pUT3418 View in Browser
ZmGRF2 GRMZM2G004619 AY109917 pUT3344 View in Browser
ZmGRF3 GRMZM2G096709 GRFTF3 pUT3415 View in Browser
ZmGRF4 GRMZM2G018414 GRFTF4 View in Browser
ZmGRF5 GRMZM2G129147 GRFTF5 pUT5949 View in Browser
ZmGRF6 GRMZM2G034876 GRFTF6 pUT6086 View in Browser
ZmGRF7 GRMZM2G098594 GRFTF7 pUT3373 View in Browser
ZmGRF8 GRMZM2G041223 GRFTF8 pUT3356 View in Browser
ZmGRF9 GRMZM2G124566 GRFTF9 pUT5948 View in Browser
ZmGRF10 GRMZM2G105335 GRFTF10 View in Browser
ZmGRF11 GRMZM5G850129 GRFTF11 pUT4728 View in Browser
ZmGRF12 GRMZM2G067743 GRFTF12 pUT3345 View in Browser
ZmGRF13 GRMZM2G045977 GRFTF13 pUT6764 View in Browser
ZmGRF14 GRMZM5G853392 GRFTF14 pUT3346 View in Browser
ZmGRF15 GRMZM2G099862 GRFTF15 pUT3370 View in Browser