GrassTFDB :: Browse Family::Rice

Displaying GRF Family from Rice


Previously, we identified a novel rice gene, GROWTH-REGULATING FACTOR1 (OsGRF1), which encodes a putative transcription factor that appears to play a regulatory role in stem elongation. We now describe the GRF gene family of Arabidopsis thaliana (AtGRF), which comprises nine members. The deduced AtGRF proteins contain the same characteristic regions--the QLQ (Gln, Leu, Gln) and WRC (Trp, Arg, Cys) domains--as do OsGRF1 and related proteins in rice, as well as features indicating a function in transcriptional regulation. Most of the AtGRF genes are strongly expressed in actively growing and developing tissues, such as shoot tips, flower buds, and roots, but weakly in mature stem and leaf tissues. Overexpression of AtGRF1 and AtGRF2 resulted in larger leaves and cotyledons, as well as in delayed bolting of the inflorescence stem when compared to wild-type plants. In contrast, triple insertional null mutants of AtGRF1-AtGRF3 had smaller leaves and cotyledons, whereas single mutants displayed no changes in phenotype and double mutants displayed only minor ones. The alteration of leaf growth in overexpressors and triple mutants was based on an increase or decrease in cell size, respectively. These results indicate that AtGRF proteins play a role in the regulation of cell expansion in leaf and cotyledon tissues.

Protein Name
accepted / suggested
Gene Locus Synonym/
Gene Name
Clone in TFome Genome Browser
OsGRF1 LOC_Os02g45570 View in Browser
OsGRF2 LOC_Os02g47280 View in Browser
OsGRF3 LOC_Os02g53690 View in Browser
OsGRF4 LOC_Os03g47140 View in Browser
OsGRF5 LOC_Os03g51970 View in Browser
OsGRF6 LOC_Os04g48510 View in Browser
OsGRF7 LOC_Os04g51190 View in Browser
OsGRF8 LOC_Os06g02560 View in Browser
OsGRF9 LOC_Os07g28430 View in Browser
OsGRF10 LOC_Os11g35030 View in Browser
OsGRF11 LOC_Os12g29980 View in Browser
OsOrphan69 LOC_Os06g10310 View in Browser