GrassTFDB :: Browse Family::Sugarcane

Displaying HSF Family from Sugarcane


Heat shock factors (HSF) are the transcriptional activators of the heat shock response. The conversion of constitutively expressed HSF to a form that can bind DNA requires the trimerization of the protein, involving leucine zipper interactions as shown for yeast, Drosophila, chicken and human HSFs. Like other metazoan HSFs, the endogenous Arabidopsis HSF displays heat shock-inducible DNA-binding activity in gel retardation assays. The heat shock-inducible binding of a recombinant Arabidopsis HSF (ATHSF1) expressed in Arabidopsis plants suggests that ATHSF1 is the major heat shock factor regulating the heat stress response. However, on transient expression in Drosophila and human cells, ATHSF1 fails to exhibit proper regulation, as demonstrated by constitutive binding to DNA, and by constitutive expression of a chloramphenicol acetyltransferase (CAT) reporter gene under the control of the Drosophila hsp70 promoter. These results suggest that the regulation of ATHSF1 is normally dependent on a specific factor that inhibits the DNA-binding and transcriptional activities under non-heat shock conditions.

Protein Name
accepted / suggested
Gene Locus Synonym/
Gene Name
Clone in TFome Genome Browser
ScHSF1 SCACAM1071D04.g View in Browser
ScHSF2 SCACCL6009B02.g View in Browser
ScHSF3 SCBGRT1046D12.g View in Browser
ScHSF4 SCCCCL5002E07.g View in Browser
ScHSF5 SCCCCL6002H05.g View in Browser
ScHSF6 SCCCLB1C06H02.g View in Browser
ScHSF7 SCCCLR1066C06.g View in Browser
ScHSF10 SCEZLB1013C01.g View in Browser
ScHSF11 SCEZRZ3016A08.g View in Browser
ScHSF12 SCMCFL5005H11.g View in Browser
ScHSF13 SCMCRZ3067A03.g View in Browser
ScHSF14 SCMCST1051D09.g View in Browser
ScHSF15 SCSBLB2037C10.g View in Browser
ScHSF16 SCSBRZ3117C06.g View in Browser
ScHSF18 SCUTST3084B04.g View in Browser
ScHSF19 PTSo00731.1 View in Browser