GrassTFDB :: Browse Family::Maize

Displaying Alfin-like Family from Maize


The Alfin1-like family is first described by its founding member, Alfin1. The cDNA of Alfin1 was obtained by differential screening of a poly(A)+ library from salt-tolerant alfalfa cells, which encodes a protein with a Cys4 and His/Cys3 putative zinc-binding domain. The putative consensus binding site for Alfin1 is shown to contain two to five G-rich triplets with the conserved core of GNGGTG or GTGGNG (PMID:9869418). Alfin1-binding sites occur in promoters of genes expressed in roots of a wide variety of plant species. Overexpression of Alfin1 in transgenic alfalfa plants driven by the CaMV 35S promoter confers a many-fold increase in root growth under normal and saline conditions and does not adversely affect shoot growth (PMID:10750899). More recent research has purported that the zinc finger motif in Alfin1 is actually a canonical plant homeodomain (PHD) finger, which has not been implicated in DNA binding in other proteins thus far. Further studies are needed to determine whether Alfin1 binds to DNA through the PHD finger or via another unidentified motif. Alfin1-like proteins in Arabidopsis thaliana have been shown to localize to the nucleus and bind to H3K4me3/2 via plant homeodomain (PHD) fingers (PMID:19154204).

Protein Name
accepted / suggested
Gene Locus Synonym/
Gene Name
Clone in TFome Genome Browser
ZmALF1 GRMZM2G148810 ALF1 pUT1441 View in Browser
ZmALF2 GRMZM2G063864 ALF2 pUT6626 View in Browser
ZmALF3 GRMZM2G038066 ALF3 View in Browser
ZmALF4 GRMZM2G153087 ALF4 pUT6507 View in Browser
ZmALF5 GRMZM2G016817 ALF5 pUT6529 View in Browser
ZmALF6 GRMZM2G115424 ALF6 pUT6662 View in Browser
ZmALF7 GRMZM2G107807 ALF7 pUT5753 View in Browser
ZmALF8 GRMZM2G172001 ALF8 pUT1500 View in Browser
ZmALF9 GRMZM2G017142 ALF9 pUT1436 View in Browser
ZmALF10 GRMZM2G050495 ALF10 pUT5755 View in Browser
ZmALF11 GRMZM2G158918 ALF11 pUT6296 View in Browser
ZmALF12 GRMZM5G893976 ALF12 pUT5779 View in Browser
ZmALF13 GRMZM2G080917 ALF13 pUT6601 View in Browser
ZmALF14 GRMZM2G156088 ALF14 pUT4122 View in Browser
ZmALF15 AC225147.4_FG003 ALF15 pUT1434 View in Browser
ZmALF16 GRMZM2G016564 ALF16 View in Browser
ZmALF17 GRMZM2G110952 ALF17 pUT6274 View in Browser
ZmALF18 GRMZM2G008259 ALF18 pUT5754 View in Browser
ZmALF19 GRMZM2G047316 ALF19 pUT6622 View in Browser