GrassTFDB :: Browse Family::Sorghum

Displaying Alfin-like Family from Sorghum


The Alfin1-like family is first described by its founding member, Alfin1. The cDNA of Alfin1 was obtained by differential screening of a poly(A)+ library from salt-tolerant alfalfa cells, which encodes a protein with a Cys4 and His/Cys3 putative zinc-binding domain. The putative consensus binding site for Alfin1 is shown to contain two to five G-rich triplets with the conserved core of GNGGTG or GTGGNG (PMID:9869418). Alfin1-binding sites occur in promoters of genes expressed in roots of a wide variety of plant species. Overexpression of Alfin1 in transgenic alfalfa plants driven by the CaMV 35S promoter confers a many-fold increase in root growth under normal and saline conditions and does not adversely affect shoot growth (PMID:10750899). More recent research has purported that the zinc finger motif in Alfin1 is actually a canonical plant homeodomain (PHD) finger, which has not been implicated in DNA binding in other proteins thus far. Further studies are needed to determine whether Alfin1 binds to DNA through the PHD finger or via another unidentified motif. Alfin1-like proteins in Arabidopsis thaliana have been shown to localize to the nucleus and bind to H3K4me3/2 via plant homeodomain (PHD) fingers (PMID:19154204).

Protein Name
accepted / suggested
Gene Locus Synonym/
Gene Name
Clone in TFome Genome Browser
SbALF1 Sb01g003420 View in Browser
SbALF2 Sb02g006980 View in Browser
SbALF3 Sb02g038980 View in Browser
SbALF4 Sb03g005320 View in Browser
SbALF5 Sb03g042180 View in Browser
SbALF6 Sb04g023220 View in Browser
SbALF7 Sb05g007010 View in Browser
SbALF8 Sb06g017810 View in Browser
SbALF9 Sb08g006530 View in Browser
SbALF10 Sb09g004740 View in Browser
SbALF11 Sb09g018350 View in Browser
SbALF12 Sb09g018370 View in Browser
SbALF13 Sb09g020610 View in Browser