GrassTFDB :: Browse Family::Sorghum

Displaying HSF Family from Sorghum


Heat shock factors (HSF) are the transcriptional activators of the heat shock response. The conversion of constitutively expressed HSF to a form that can bind DNA requires the trimerization of the protein, involving leucine zipper interactions as shown for yeast, Drosophila, chicken and human HSFs. Like other metazoan HSFs, the endogenous Arabidopsis HSF displays heat shock-inducible DNA-binding activity in gel retardation assays. The heat shock-inducible binding of a recombinant Arabidopsis HSF (ATHSF1) expressed in Arabidopsis plants suggests that ATHSF1 is the major heat shock factor regulating the heat stress response. However, on transient expression in Drosophila and human cells, ATHSF1 fails to exhibit proper regulation, as demonstrated by constitutive binding to DNA, and by constitutive expression of a chloramphenicol acetyltransferase (CAT) reporter gene under the control of the Drosophila hsp70 promoter. These results suggest that the regulation of ATHSF1 is normally dependent on a specific factor that inhibits the DNA-binding and transcriptional activities under non-heat shock conditions.

Protein Name
accepted / suggested
Gene Locus Synonym/
Gene Name
Clone in TFome Genome Browser
SbHSF1 Sb01g000730 View in Browser
SbHSF2 Sb01g005250 View in Browser
SbHSF3 Sb01g008380 View in Browser
SbHSF4 Sb01g021490 View in Browser
SbHSF5 Sb01g034500 View in Browser
SbHSF6 Sb01g042370 View in Browser
SbHSF7 Sb01g046350 View in Browser
SbHSF8 Sb02g004370 View in Browser
SbHSF9 Sb02g026500 View in Browser
SbHSF10 Sb02g026590 View in Browser
SbHSF11 Sb02g030490 View in Browser
SbHSF12 Sb02g040790 View in Browser
SbHSF13 Sb03g025770 View in Browser
SbHSF14 Sb03g028470 View in Browser
SbHSF15 Sb03g033750 View in Browser
SbHSF16 Sb03g034630 View in Browser
SbHSF17 Sb04g008300 View in Browser
SbHSF18 Sb04g020050 View in Browser
SbHSF19 Sb04g021490 View in Browser
SbHSF20 Sb06g025710 View in Browser
SbHSF21 Sb07g025120 View in Browser
SbHSF22 Sb09g026440 View in Browser
SbHSF23 Sb10g021800 View in Browser
SbHSF24 Sb10g022340 View in Browser